A correct diagnosis of Parkinson’s disease (PD) is important for prognosis and therapeutic management, as well as for clinical research.
Tag Archives: Parkinson’s Disease
Queen Square Brain Bank (QSBB) criteria for PD diagnosis
Table 1: Queen Square Brain Bank UK PDS Brain Bank Criteria for the diagnosis of Parkinson’s disease Step 1 Diagnosis of parkinsonian syndrome – MUST BE PRESENT Bradykinesia (slowness of initiation of voluntary movement with progressive reduction in speed and amplitude or repetitive actions)* and at least one of the following: Muscular rigidity 4- to 6-Hz rest tremor Postural instability
Practical recommendations for treatment of early untreated PD
The choice of drugs depends on a risk/benefit evaluation based on: The ability to improve motor disability (better with levodopa) The risk of motor complications (more common in younger patients; delayed by agonists) The risk of neuropsychiatric complications (more common in older and cognitively impaired patients; greater with agonists) Medications for the treatment of de novo patients MAO-B inhibitors (Level
Rolpryna SR
Company: KRKA Pharma Dublin Ltd.
Oprymea
Company: KRKA Pharma Dublin Ltd.
Recognition and excellence hand-in-hand
Aoife Connors reports on how winning an Irish Healthcare Award helped raise awareness of Parkinson’s disease, mental health and a primary care initiative.
Research to shed light on impulse control in Parkinson’s disease
Impulse control disorders amongst patients with Parkinson’s disease on dopamine replacement therapy present a “unique opportunity” for research into the neurobiology of impulsive behaviour, researchers say.
Miramel
Company: Clonmel Healthcare Ireland.
Prapexin
Company: Rowex Ltd.
‘Social cognition’ impaired in early Parkinson’s disease
Patients with early Parkinson’s disease can have subtle deficits in the way they interpret the intentions and feelings of others, which may have an adverse effect on their social interactions and quality of life.