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A perspective on prescribing BZDs and Z-drugs

All living organisms appear to have circadian rhythms and sleep is integral to these rhythms. Evolution has mandated that for almost 30 per cent of our lives, we sleep. This process presumably began with the emergence of unicellular life forms almost four billion years ago, and our own distinct pattern no doubt evolved from early hominids almost five million years ago. We have a planet that rotates on its axis once every 24 hours, approximately, resulting in periods of light and darkness. These would have been almost of equal length around equatorial Africa, where early man is thought to have…