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Crohn’s disease — a clinical review, part 2

In part two of an extensive look at Crohn’s disease, Prof Calvin Coffey and Mr Rishabh Sehgal look at medical and surgical management of the condition, as well as exploring some novel therapeutic targets

The evolution of medical treatment for Crohn’s disease

Dr Karen Hartery, Senior Clinical Fellow in Gastroenterology, currently working in John Radcliffe Hospital, Oxford University Hospital Trust, looks back at more than 100 years of Crohn’s disease — a condition that was first recorded in 1913 Although the initial case series was described in 1913 by a Scottish surgeon, Thomas Kennedy Daiziel, the landmark paper that brought Crohn’s disease

Team studies 12-week recovery programme

Dr Juliette Hussey has sought to assess the effect of a diet and exercise rehabilitation plan aimed at helping patients recovering from surgery for cancer of the oesophagus to return to pre-cancer levels of activity and performance.

GORD can lead to cancer risk factors

The British Society of Gastroenterology defines dyspepsia as a group of symptoms that alert doctors to consider disease of the upper gastrointestinal (GI) tract, and states that dyspepsia itself is not a diagnosis.

Moving beyond clinical remission

Early diagnosis of Inflammatory Bowel Disease is key and GPs play an important role, Gary Culliton writes in his latest Clinical Update.

Medication, surgery both effective

Delineating symptoms is extremely important in terms of later management of gastro-oesophageal reflux disease (GORD), Gary Culliton reports in his latest Clinical Update.

Use of laparoscopic resection is not supported

Among patients with stage II or III rectal cancer, the use of laparoscopic resection compared with open resection fails to meet the criterion for non-inferiority for pathologic outcomes, according to research published in JAMA.

Value in use of FODMAP diet for IBS questioned

There is very little evidence to recommend avoiding certain types of dietary carbohydrate, known as the FODMAP diet, to ease the symptoms of irritable bowel syndrome (IBS), concludes a review of the available data in Drug and Therapeutics Bulletin (DTB).