Significant Benefits of Bedtime Therapy Variation in blood pressure levels display circadian rhythms, with a morning surge in blood pressure (BP) known to increase the risk of myocardial events in the first several hours post awakening. Time of ingestion of hypertension medications can affect this circadian pattern of BP, and there is emerging evidence that [...]
2011 NICE Hypertension Guidelines Updated NICE guidelines on hypertension1, published in October last year in conjunction with the British Hypertension Society (BHS), recommend that a diagnosis of hypertension should be made using 24-hour ambulatory blood pressure monitoring (ABPM). The process involves wearing a type of mobile blood pressure monitor that straps around the waist and [...]
Adapted from the presentation ‘COPD – Where are we now?’, which took place at the Frontiers in Respiratory Medicine meeting, October 21st, 2011. MIMS Ireland Copyright®
Prevalence Moderate and Severe COPD affects one in 10 people The prevalence of COPD is increasing in Ireland, and COPD is expected to be the third cause of death by 2020. BOLD, a worldwide study including close to 10,000 participants, aimed to measure the prevalence of COPD, its risk factors and their variation across countries [...]
Towards endotype-specific therapy Phenotypes vs Endotypes One way to classify asthma involves identifying the phenotypes of asthma – that is the clusters of properties observed in different types of asthma. Criteria related to clinical aspects (e.g. severity and frequency of exacerbations, airflow restriction, age of onset, treatment effect), type of inflammatory cells (eosinophils or neutrophils) [...]
Effects of early nutritional interventions on the development of atopic disease in children Major Recommendations The following recommendations summarise the current evidence related to allergy prevention through dietary interventions, keeping in mind that some aspects are currently uncertain due to inadequate study design or paucity of data. 1. There is a current lack of evidence [...]
Infant formulae are increasingly being supplemented with probiotics, prebiotics, or both (see box for definitions). Recommendations for using probiotic- and/or prebiotic-supplemented formulae should be determined by their nutritional adequacy, potential short- and long-term benefits, and safety of continued administration. The Committee on Nutrition of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) systematically [...]
New results from the HELENA study show that vitamin D deficiency is a highly prevalent condition in European adolescents. HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) is a wide-ranging project financially supported by the European Union, which is designed to understand and enhance nutritional and lifestyle habits of adolescents in Europe. The nutritional [...]
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