The health benefits of smoking cessation are well documented. Smokers who quit reduce their risk of cardiovascular disease, lung disease, and cancer and increase their life expectancy substantially. While most smokers make several quit attempts before they succeed, about one in four who use any pharmacotherapy will eventually quit smoking. Evidence indicates that pharmacotherapy increases [...]
Use of prescribed drugs to treat alcohol addiction
Opioid misuse
PHARMACOLOGY OF OPIOIDS The term ‘opioids’ refers to a class of psychoactive substances derived from the poppy plant (including opium, morphine and codeine), as well as semi-synthetic forms (including heroin) and synthetic compounds (including methadone and buprenorphine) with similar properties. Illicit use of opioids generally involves injecting, or inhaling the fumes produced by heating the [...]
Oral Bisphosphonates and Risk of Oesophageal Cancer
Oral bisphosphonates are primarily indicated for the prevention and/or treatment of osteoporosis and products currently authorised for use in Ireland include alendronate, ibandronate and risedronate. Some oral bisphosphonates are indicated only for Paget’s disease (tiludronate) or for treatment in malignancy indications (clodronate). The Pharmacovigilance Working Party (PhVWP) of the European Medicines Agency recently reviewed new [...]
Cimzia
Company: UCB (Pharma) Ireland Ltd. Legal category: Prescription. High Tech. Sport permitted. Active ingredient: Certolizumab pegol 200mg/ml. Description: Solution for injection in pre-filled syringe. Presentation: 2 per pack. Prices on request. Indications: Treatment of moderate to severe, active rheumatoid arthritis in combination with methotrexate (MTX) when the response to disease-modifying antirheumatic drugs including MTX has [...]
Docetaxel Actavis
Company: Actavis Ireland Ltd. Legal category: Prescription. Hospital. Sport permitted. Active ingredient: Docetaxel 20mg/ml. Description: Concentrate for solution for infusion. Presentation: 1ml; 4ml; 7ml. Prices on request. Indications: Adjunct to operable node-positive breast cancer. Metastatic breast cancer in patients whose tumours overexpress HER2 in combination with trastuzumab without prior chemotherapy. Locally advanced or metastatic breast [...]
Mycolat
Company: Rowex Ltd. Legal category: Prescription. High Tech. Sport permitted. Active ingredient: Mycophenolate mofetil 250mg, 500mg. Description: 250mg: Hard gelatin capsules with blue cap and orange body. 500mg: Lavender, biconvex, film-coated tablets. Presentation: 250mg-100, €97.58; 500mg-50, €97.58. Indications: In combination with ciclosporin and corticosteroids for the prophylaxis of acute transplant rejection in patients receiving allogeneic [...]
Nebivolol Teva
Company: Teva Pharmaceuticals Ireland. Legal category: Prescription. GMS. Prohibited in specific sports. Active ingredient: Nebivolol (HCl) 5mg. Description: White/off-white, round, cross-scored tablet. Presentation: 28, €9.73. Indications: Treatment of essential hypertension and of stable mild and moderate chronic heart failure (CHF) in addition to standard therapies in elderly patients 70 years or older. Pharmacology: Nebivolol is [...]
Changes to Augmentin
GlaxoSmithKline Ireland wishes to inform you of changes made to their Augmentin range. These changes arise from a European regulatory review which concluded that there is a need to harmonise the prescribing information for Augmentin. The main changes are: • The licensed indication is dependent on the ratio of the active ingredients • A 2:1 [...]