FACTS ABOUT RHEUMATOID ARTHRITIS • Rheumatoid arthritis (RA) is a chronic progressive autoimmune inflammatory disease. It is a progressive disabling condition characterised by persistent joint synovial tissue inflammation with an increase in the number of synovial cells (hyperplasia), infiltration by white blood cells and formation of new blood vessels. As a result, the synovium becomes [...]
• Drug management of RA aims to relieve symptoms and to modify the disease process. • Pain relief is the number one priority for patients with RA. • Radiological progression is closely correlated with progressive functional impairment. The aim of disease modification is to slow or stop radiological progression. • Conventional drug therapy involves various [...]
• Over 80% of cancer patients with advanced metastatic disease suffer pain, caused mostly by direct tumour infiltration. • Pain undermines quality of life considerably and is a clinically important indicator of tumour progression. • Cancer pain may be acute or chronic and should be addressed accordingly. • Approximately 20% of pain in cancer patients [...]
Isotretinoin is authorised for oral use for the treatment of severe forms of acne (such as nodular or conglobate acne or acne at risk of permanent scarring) resistant to adequate courses of standard therapy with systemic antibacterials and topical therapy. Isotretinoin should only be prescribed by or under the supervision of a physician with expertise [...]
Coadministration of methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs) can cause a pharmacokinetic interaction and a subsequent increase in blood methotrexate concentrations. NSAID-induced increases in methotrexate concentrations are due to: Decreased glomerular filtration of methotrexate by NSAIDs via the reduction of renal blood flow with inhibition of prostaglandin synthesis. Inhibition of methotrexate tubular secretion. Competition for [...]
Company: GlaxoSmithKline. Legal category: Prescription. GMS. Sport permitted. Active ingredients: Dutasteride 0.5mg, tamsulosin (HCl) 0.4mg. Description: Hard brown/orange capsules imprinted with GS 7CZ. Presentation: 30, €22.90. Indications: Treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH). Reduction in the risk of acute urinary retention and surgery in patients with moderate to severe symptoms [...]
Company: sanofi-aventis Ireland Ltd. Legal category: Prescription. GMS. Sport permitted. Active ingredients: Clopidogrel (hydrogen sulphate) 75mg, acetylsalicylic acid (ASA) 75mg. Description: Yellow, oval film-coated tablet marked C75 on one side and A75 on reverse. Presentation: 28, €36.44. Indications: Prevention of atherothrombotic events in patients already taking both clopidogrel and ASA for continuation in therapy in [...]
Company: Pinewood Healthcare. Legal category: Prescription. GMS. Sport permitted. Active ingredient: Esomeprazole (magnesium dihydrate) 20mg, 40mg. Description: Slightly pink or off-pink gastro-resistant hard capsules, resp. Presentation: 20mg, €20.93; 40mg, €30.92. Indications: Treatment of erosive reflux oesophagitis (RO); long-term management of healed oesophagitis to prevent relapse; symptomatic treatment of gastroesophageal reflux disease (GORD). [...]
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