1. An abnormal digital rectal exam result or elevated serum PSA measurement could indicate prostate cancer. The exact cut-off level of what is considered to be a normal PSA value has not yet been determined, but values around < 2.5–3ng/ml are often used for younger men. ( C ) 2. The diagnosis of prostate cancer [...]

Deferred Treatment The rationale for deferred treatment is that prostate cancer often progresses slowly, and is diagnosed in older men in whom there is a high incidence of co-morbidity and related high competitive mortality. Watchful waiting can be considered as an option for treating patients with localised prostate cancer in whom life expectancy is limited [...]

A recent survey by Astellas Pharma Co. Ltd researched patients’ access to information, treatment options provided upon diagnosis, treatment decision support and general patient care management. Entitled “Silent Voices”, the survey took place in France, Italy, Spain, Poland, Germany and Ireland and researched 50 prostate cancer patients in each country. It was undertaken in Ireland [...]

Reference: Wespes, E. et al. Guidelines on male sexual dysfunction: Erectile Dysfunction and Premature Ejaculation. European Association of Urology. 2009. Available at www.uroweb.org. Accessed 12/5/2010.

The emergence of oral therapy to treat erectile dysfunction (ED) has forever changed the field of male sexual health. While the evaluation and management of ED was primarily in the domain of urologists, now the primary care provider is often the initial evaluator and prescriber of therapy and the urologist typically sees patients where oral [...]

Sildenafil (Viagra) Onset and duration: • Tmax 30-120 min • Median 60 min • Duration: 4 hrs • Food decreases absorption Dose: • 25-100mg • Initially 50mg Metabolism: • Metabolised by CYP3A4 (major route), 2C9 (minor route) • Concomitant 3A4 inhibitors associated with increased levels. Starting dose: 25mg • Concomitant ritonavir not advised • Severe [...]