February 9, 2012

Second phase III study of Avastin

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Second phase III study of Avastin in 1st line metastatic breast cancer meets its primary endpoint – Roche has recently announced that a phase III study in metastatic breast cancer investigating Avastin (bevacizumab) in combination with docetaxel chemotherapy compared to docetaxel alone, met its primary endpoint of improving the time patients live without their disease [...]

New review highlights Femara benefits

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New review highlights Femara benefits in terms of reduction of the risk of distant relapse in women with hormone-sensitive breast cancer – A new review underlining the significance of distant metastases in breast cancer outcomes highlights the benefits of aromatase inhibitors in women with hormone-sensitive early breast cancer. Femara is more effective in the neoadjuvant [...]

Seroquel XR once-daily prolonged tablets

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Seroquel XR once-daily prolonged tablets for the treatment of schizophrenia – AstraZeneca announced last month the Irish launch of Seroquel XR (quetiapine fumarate) Prolonged-Release Tablets, a once-daily medicine for the treatment of schizophrenia in adult patients. Schizophrenia is a serious brain disorder with symptoms including distorted perceptions of reality, hallucinations and delusions, illogical thinking, and [...]

Nilotinib Is Highly Active and Safe

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Nilotinib Is Highly Active and Safe in Chronic Myelogenous Leukaemia Patients with Imatinib-Resistance or Intolerance – New data demonstrated the efficacy and tolerability of Tasigna (nilotinib) in the treatment of Chronic myelogenous leukaemia (CML) patients with Imatinib-Resistance or Intolerance for whom there are few therapeutic options. CML is a myeloproliferative disorder resulting from a chromosomal [...]

Zevalin Receives Positive CHMP Opinion

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Zevalin Receives Positive CHMP Opinion in Europe for First-Line Consolidation Treatment – Bayer Schering Pharma AG has received a positive opinion from the European Committee for Medicinal Products for Human Use (CHMP) recommending Zevalin ([90Y]-ibritumomab tiuxetan) as consolidation therapy after remission induction in previously untreated patients with follicular lymphoma in Europe. Consolidation therapy is a [...]

MIMS Ireland – Change in Pricing Policy

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Following changes introduced by the HSE for the reimbursement of medicines under the various HSE community schemes, and as MIMS Ireland relies on manufacturers for the prices published with entries, the pricing policy of MIMS Ireland has changed. From May 2008 our pricing policy is as follows: • Primary Care Reimbursement Service (PCRS or ‘GMS’) [...]

Ixprim

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Company: Grünenthal Pharma Ltd. Legal category: Prescription. GMS (from May 6th). Sport permitted. Active ingredient: Tramadol hydrochloride 37.5mg, paracetamol 325mg Description: Pale yellow film coated-tablets. Presentation: 60, €13.20. Indications: Treatment of moderate to severe pain requiring a combination of tramadol and paracetamol. Pharmacology: Tramadol is an opioid analgesic acting on the central nervous system. Tramadol [...]

Retacrit

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Company: Hospira Ireland Ltd. Legal category: Prescription. Sport prohibited. Active ingredient: Epoetin zeta (recombinant human erythropoietin) 3333 IU/ml, 10000 IU/ml, 40000 IU/ml. Description: Clear, colourless solution for injection in pre-filled syringe. Presentation: 1000 IU/0.3ml-6, €54.59; 2000 IU/0.6ml-6, €104.82; 3000 IU/0.9ml-6, €155.05; 4000 IU/0.4ml-6, €203.83; 5000 IU/0.5ml-6, €272.98; 6000 IU/0.6ml-6, €314.47; 8000 IU/0.8ml-6, €436.76; 10000 IU/1ml-6, [...]

Tasigna

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Company: Novartis Ireland Ltd. Legal category: Prescription. Sport permitted. Active ingredient: Nilotinib 200mg (as hydrochloride monohydrate). Description: White to slightly yellowish powder in light yellow opaque hard gelatine capsules, size 0 with red axial imprint NVR/TKI. Presentation: 112, price available on request. Indications: Treatment of adults with chronic phase and accelerated phase Philadelphia chromosome positive [...]

Trimoptin

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Company: Athlone Laboratories Ltd. Legal category: Prescription. GMS. Sport permitted. Active ingredient: Trimethoprim 200mg Description: Flat, white, bevelled-edge tablets embossed TR 200. Presentation: 100, €12.20. Indications: Treatment of infections caused by susceptible organisms including most gram-positive and gram-negative aerobic organisms (H. influenza, S. pneumoniae, K. pneumoniae, S. aureus, E. coli, S. faecalis, Enterobacter and Proteus [...]

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