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November 26, 2014

Spiriva Respimat – New Indication for Treatment of Asthma

Download pdf Spiriva Respimat (tiotropium) is now indicated for add-on maintenance bronchodilator treatment in adults with asthma currently treated with inhaled corticosteroids (≥800mcg daily of budesonide or equivalent) and long-acting ß2 agonists (LABAs) and who experienced one or more severe exacerbations in the previous year.1 It is already licensed for maintenance bronchodilator treatment in patients […]

Jardiance – Approved for Treatment of Type 2 Diabetes

Download PDF Boehringer Ingelheim Ireland Ltd. and Eli Lilly and Co. Ireland Ltd. are pleased to announce that Jardiance (empagliflozin) has been granted European marketing authorisation for the treatment of type 2 diabetes. Empagliflozin is a potent and selective inhibitor of sodium-glucose co-transporter 2 (SGLT2) which is predominantly responsible for renal glucose reabsorption. Empagliflozin acts […]

Individualised Therapy in Type 2 Diabetes

Download PDF The Global Partnership for Effective Diabetes Management advocates an individualised therapeutic approach and has identified specific type 2 diabetes patient subgroups that require special consideration and proposed practical advice for setting glycaemic targets and tailoring treatment management for these groups. A patient-centred approach has also been recommended by several other organisations, such as […]

New Treatment Option for Type 2 Diabetes – SGLT2 Inhibitors

Download PDF Sodium glucose co-transporter 2 (SGLT2) inhibitors are a new class of drugs indicated in the treatment of type 2 diabetes mellitus to improve glycaemic control in adults aged ≥18 years as monotherapy when diet and exercise alone do not provide adequate glycaemic control when use of metformin considered inappropriate due to intolerance, or […]

Transdermal Fentanyl – Reminder about the Potential for Life-Threatening Harm from Accidental Exposure

The European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) recently completed a review of global reports of accidental exposure to transdermal fentanyl patches. Accidental exposure to transdermal fentanyl can occur if a patch is swallowed or transferred to another individual. The recent review emphasised the need for safe handling of patches. Children are at risk […]

Adverse Reaction Reporting during 2013

The HPRA continues to place great emphasis on encouraging and promoting the submission of adverse reaction reports associated with the use of medicines from its stakeholders. These reports are important to signal potential safety issues from medicines in use and ultimately assist the HPRA in monitoring the safety of medicines on the Irish market.   […]

Eplerenone Rowex

Company: Rowex Ltd. Legal category: Prescription. GMS. Sport prohibited. Active ingredient: Eplerenone 25mg, 50mg. Description: Light yellow, round, biconvex film-coated tablets marked E9RN on one side and strength on reverse. Presentation: €22.40. Indication: In addition to standard therapy including beta-blockers, in stable patients with left ventricular dysfunction (LVEF ≤40 %) to reduce the risk of […]

Treclinac

Company: Meda Health Sales. Legal category: Prescription. GMS. Sport permitted. Active ingredients: Clindamycin (as phosphate)/tretinoin 1% w/w/0.025% w/w. Description: Gel. Presentation: 30g, €14.50. Indication: Topical treatment of acne vulgaris (comedones, papules, pustules). Pharmacology: Clindamycin is a semisynthetic derivative of the parent compound lincomycin produced by Streptomyces lincolnensis and is predominantly bacteriostatic. It binds to the […]

Coverdine

Company: Servier Laboratories (Ireland) Ltd. Legal category: Prescription. GMS. Sport prohibited. Active ingredient: Perindopril arginine/indapamide/amlodipine besilate 5mg/1.25mg/5mg, 5mg/1.25mg/10mg, 10mg/2.5mg/5mg, 10mg/2.5mg/10mg. Description: White, oblong, film-coated tablets marked with Servier logo on one side and three horizontal, parallel lines followed by 2, 3, 4 or 5 on reverse, respectively. Presentation: 5mg/1.25mg/5mg-30, €17.71; 5mg/1.25mg/10mg-30, €19.37; 10mg/2.5mg/5mg-30, €24.42; 10mg/2.5mg/10mg-30, […]

Jakavi ▼

Company: Novartis Ireland Limited. Legal category: Prescription. High tech. Sport permitted. Active ingredient: Ruxolitinib (as phosphate) 5mg, 15mg, 20mg. Description: Round, ovaloid or elongated, curved, white tablets marked NVR on one side and L5, L15 or L20 on reverse, respectively. Presentation: 56, price available on request. Indications: Treatment of disease-related splenomegaly or symptoms with primary […]

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