Significant Benefits of Bedtime Therapy Variation in blood pressure levels display circadian rhythms, with a morning surge in blood pressure (BP) known to increase the risk of myocardial events in the first several hours post awakening. Time of ingestion of hypertension medications can affect this circadian pattern of BP, and there is emerging evidence that [...]
Critical Influence of Time of Day of Blood Pressure-lowering Treatment
Radical Change in BP Diagnosis and Treatment
2011 NICE Hypertension Guidelines Updated NICE guidelines on hypertension1, published in October last year in conjunction with the British Hypertension Society (BHS), recommend that a diagnosis of hypertension should be made using 24-hour ambulatory blood pressure monitoring (ABPM). The process involves wearing a type of mobile blood pressure monitor that straps around the waist and [...]
Lucentis approved for visual impairment due to retinal vein occlusion
Lucentis (ranibizumab) is now approved to treat visual impairment due to macular oedema secondary to retinal vein occlusion (including branch RVO or central RVO). Retinal vein occlusion (RVO) is the second most common retinal vascular disorder after diabetic retinopathy. Occlusion of the outflow channel of the retinal circulation markedly increases intraluminal venous pressure, resulting in [...]
Citalopram and Escitalopram – Risk of QT interval prolongation
Products include: Cipramil/Bellcital/Ciprager/Ciprapine/Ciprotan/Citalopram Actavis/Citalopram Teva/ Citrol and Lexapro/Escipriex/Escitalpro/Escitomar Citalopram and escitalopram are selective serotonin reuptake inhibitors (SSRIs) indicated in the treatment of depressive illness (see the Summaries of Product Characteristics (SPCs) for full details of licensed indications). Following a review of the available information on the risk of QT prolongation with these medicines, the Pharmacovigilance [...]
Budenofalk Granules
Company: Dr Falk Pharma UK Ltd. Legal category: Prescription. GMS. Sport prohibited in competition. Active ingredient: Budesonide 9mg. Description: Gastro-resistant granules. Presentation: 60 sachets, €177.20. Indication: Induction of remission in patients with active collagenous colitis. Pharmacology: The exact mechanism of budesonide in the treatment of inflammatory bowel diseases is not fully understood. Data from clinical [...]
Conbriza
Company: Pfizer Healthcare Ireland. Legal category: Prescription. GMS. Sport prohibited. Active ingredient: Bazedoxifene 20mg. Description: White, capsule shaped, film coated tablet marked WY20 on one side. Presentation: 28, €20.86. Indications: Treatment of postmenopausal osteoporosis in women at increased risk of fracture. Pharmacology: Bazedoxifene belongs to a class of compounds known as selective estrogen receptor modulators [...]
Flucloxacillin GAP
Company: Athlone Laboratories Ltd. Legal category: Prescription. GMS. Sport permitted. Active ingredient: Capsules: Flucloxacillin Na+ 250mg, 500mg. Oral solution: Flucloxacillin Na+ 125mg/5ml, 250mg/5ml. Description: Capsules: Opaque caramel body and opaque grey cap marked FXN250 and FXN500. Oral solution: Pink powder for oral solution. Presentation: Capsules: 250mg-100, €15.38; 500, €76.99; 500mg-100, €30.78; 500, €153.99. Oral solution: [...]
Konverge Plus
Company: A. Menarini Pharmaceuticals Ireland Ltd / Daiichi Sankyo Ltd. Legal category: Prescription. GMS. Sport prohibited. Active ingredients: Olmesartan medoxomil/amlodipine besilate/hydrochlorothiazide, 20/5/12.5mg, 40/5/25mg, 40/10/25mg. Description: Light orange, light yellow or greyish red film-coated tablets marked C51, C54 or C57 on one side respectively. 20/5/12.5mg: Round. 40/5/25mg, 40/10/25mg: Oval. Presentation: 20/5/12.5mg-28, €22.70; 40/5/25mg-28, €29.11; 40/10/25mg-28, €29.96. [...]
Latop
Company: Rowex Ltd. Legal category: Prescription. GMS. Sport permitted. Active ingredient: Latanoprost 50mcg/ml. Description: Eye drops solution. Presentation: 2.5ml-1, €16.15. Indications: Reduction of elevated intraocular pressure (IOP) in patients with open angle glaucoma and ocular hypertension. Reduction of elevated IOP in paediatric patients with elevated IOP and paediatric glaucoma. Pharmacology: Latanoprost, a prostaglandin F2α analogue, [...]