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June 25, 2016

Diagnosis and Treatment of Benign Prostatic Hyperplasia

DIAGNOSIS OF BENIGN PROSTATIC HYPERPLASIA1   BPH and complications Benign prostatic hyperplasia (BPH), also called benign prostatic hypertrophy, is a histologic diagnosis characterised by proliferation of prostate cells. Complications related to bladder outlet obstruction (BOO) secondary to BPH include: Urinary retention Renal insufficiency Recurrent urinary tract infections Gross haematuria Bladder calculi Renal failure or uraemia […]

Agents used in the Treatment of Benign Prostatic Hyperplasia

In current clinical practice, most patients with BPH do not present with obvious surgical indications; they often have milder LUTS which is initially managed with medical therapy. Starting over 3 decades ago with the use of non-selective alpha-blockers such as phenoxybenzamine, the medical therapeutic options for BPH have since evolved significantly, giving rise to the […]

Asthma Control and Management

The Global Initiative for Asthma (GINA) characterises asthma as a chronic inflammatory respiratory condition with intermittent symptoms such as wheezing, shortness of breath, chest tightness and cough. These respiratory symptoms vary over time and in severity, along with variable expiratory airflow limitation.1   Asthma in Ireland – Facts and Figures 470,000 people are living with […]

Prevention of COPD exacerbations

Exacerbations are important events in COPD because they dramatically impair a patient’s quality of life, hasten the rate of deterioration of lung function, and contribute to significant mortality (especially in patients requiring admission to hospital) and to high cost of care. 1   A study examining if exacerbations in patients with mild COPD, or similar […]

Diagnosis and Treatment Algorithm for Evaluating and Managing Patients with Allergic Rhinitis

Click on image to enlarge   Figure 2. Overview of Common Clinical Scenarios in Allergic Rhinitis   Reference: 1. Seidman et al. Clinical Practice Guideline: Allergic Rhinitis. Otolaryngology – Head and Neck Surgery 2015, Vol. 152(1S) S1 – S43.

Overview of Common Clinical Scenarios in Allergic Rhinitis

Click on image to enlarge   Figure 1. Diagnosis and Treatment Algorithm for Evaluating and Managing Patients with Allergic Rhinitis   Reference: 1. Seidman et al. Clinical Practice Guideline: Allergic Rhinitis. Otolaryngology – Head and Neck Surgery 2015, Vol. 152(1S) S1 – S43.

Withdrawal of Fusafungine-Containing Medicinal Products

Fusafungine-containing medicinal products (i.e. Locabiotal 1% solution) for oromucosal and nasal use will no longer be available in Ireland and across the EU as the marketing authorisations (i.e. licenses) for these products are being revoked. The European Medicines Agency (EMA) Pharmacovigilance Risk Assessment Committee (PRAC) recently completed a review of the available data for these […]

Risk of Pneumonia with Inhaled Corticosteroids for Chronic Obstructive Pulmonary Disease (COPD)

The European Medicines Agency’s (EMA) Pharmacovigilance Risk Assessment Committee (PRAC) has concluded its review of the known risk of pneumonia associated with inhaled corticosteroid (ICS) medicines when used to treat COPD.   The PRAC review confirmed that COPD patients treated with ICS medicines are at increased risk of pneumonia; however the Committee’s view was that […]

Enstilar

Company: LEO Pharma. Legal category: Prescription. GMS reimbursable. Sport permitted. Active ingredients: Calcipotriol (as monohydrate)/betamethasone (as dipropionate) 50mcg/0.5mg per gram. Description: Cutaneous foam. Presentation: 60g, price available on request. Indication: Topical treatment of psoriasis vulgaris. Pharmacology: Calcipotriol is a vitamin D analogue. It induces differentiation and suppresses proliferation of keratinocytes. It also has an immunomodulatory […]

Envarsus

Company: Chiesi Ltd. Legal category: Prescription. High tech reimbursable. Sport permitted. Active ingredient: Tacrolimus (as monohydrate) 0.75mg, 1mg, 4mg. Description: Oval, white, uncoated prolonged-release tablets marked with strength on one side and TCS on reverse. Presentation: 0.75mg-30, €47.14, 1mg-30, €62.86; 4mg-30, €251.42. Indications: Prophylaxis of transplant rejection in kidney or liver allograft recipients. Treatment of […]

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