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Smoking is major factor in choice of contraception
Clinical Update - Contraception: Many of the earlier contraceptive pills had much higher dosages than the more recently introduced pills on the market. The newer pills have very low doses of oestrogen and different types of progesterone.
The aim is to produce progesterones which are effective contraceptives with minimal side effects.
In selecting a method of contraception, smoking is a major factor in assessing the risk of thrombosis. The pill increases the risk of a thrombotic event above that of the background population, but the absolute risk of thrombosis occuring is still low — only a small number per 100,000 people.
“In this context, smoking significantly increases the risk of getting a clot. In a woman who is a non-smoker, I have no problem using any of the pills – including the combined pill – up to the menopause,” said Dr Richard Horgan, Clinical Research Fellow and Specialist Registrar in Obstetrics and Gynaecology at Cork University Maternity Hospital.
The combined pill also has a protective effect against ovarian cancer. The modern combined contraceptive pill inhibits ovulation.
Many steroid hormones have similar properties and common pathways and often an enzyme reaction converts one into another. There are different orders of progesterone. “Some are more thrombogenic, some are more androgenic (they may lead to acne and hair growth),” said Dr Horgan.
The progesterone-only pill can cause irregular bleeding as one of its side effects. Weight can also be added when using the combined oestrogen/progesterone pill.
For Dr Shirley McQuade, Medical Director of the Dublin Well Woman Centre, the combined pill is still the standard oral contraceptive. The combined pill gives a regular cycle and a withdrawal bleed once a month.
A lot of women will have minor side effects when put on any pill. Progesterone can cause fluid retention, headaches, breast tenderness and bloating.
People who continue to have fluid retention- type problems usually are better if they use treatments such as Yasmin (Yasminelle is a lower dose version) or Yaz, which was released this year. Drospirenone is the progesterone that is in Yasmin.
Posted in Genito-urinary on 20 November 2009
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