Clinical Update: Type 1 Diabetes – A continuous glucose monitoring system (CGMS) uses a sensor that is inserted under the skin. It measures interstitial glucose levels, which have been shown to correlate well with plasma glucose – though there is a lag time of seven-to-12 minutes. It measures average glucose every five minutes for around [...]
Clinical Update: Type 1 Diabetes – The biggest fear that that type I diabetics have, in their daily lives, is hypoglycaemia, says UCC-based Consultant Endocrinologist, Prof Brendan Buckley. This may compromise diabetic control significantly in many patients. “Reliable, affordable continuous glucose monitors would represent a huge advance through being able to predict impending hypoglycaemia, by [...]
Clinical Update: Type 1 Diabetes – Good glucose control before and during pregnancy makes a huge difference to pregnancy outcome. If a woman conceives during a period of poor diabetic control, poor pregnancy outcomes are more likely. Birth defects in women with pre-gestational diabetes can be up to three or four times the background rate, [...]
Patients who quit cigarette smoking are at a higher risk of developing type 2 diabetes, a new study has found. Although quitting smoking reduces the risk of lung cancer and cardiovascular disease, the decision to quit does not come without its own risks, the researchers found. The primary link of diabetes is the weight gain [...]
Clinical Update – Diabetes: It is a very exciting time for the management of type 2 diabetes. New medications are being used and they do make a difference, Dr Diarmuid Smith, Consultant Endocrinologist at Dublin’s Beaumont Hospital, believes. Many diabetes specialists express satisfaction with metformin, sulphonureas and insulin, and there is long-term data supporting their [...]
Clinical Update – Diabetes: Bariatic surgeons have been aware for some time that the effects of bypass surgery on diabetes are dramatic. Traditionally, patients referred for such surgery have had a BMI of 35kg/m2 and above. Improvement has been observed in the diabetes of 100 per cent of gastric bypass patients who have undergone this [...]
Clinical Update – Diabetes: Two papers have recently been published on the mitochondrial peptide Humanin (HN), in relation to insulin action. This peptide has an effect on insulin sensitivity. It suppresses hepatic glucose production and increases glucose uptake into the periphery tissues, such as muscle. “This peptide is potent but it is early days,” said [...]
Dr Colin Davenport examines the role of the incretin class of drugs in offering glycaemic control and weight loss in type 2 diabetic mellitus patients Type 2 Diabetes Mellitus (T2DM) is a complex disorder caused by multiple predisposing genes combined with obesity and a sedentary lifestyle. On diagnosis of the disease, affected individuals are encouraged [...]
Novo Nordisk presented the latest data on its new diabetes drug at the 45th Annual Meeting of the European Association for the Study of Diabetes (EASD). Niamh Mullen reports from Vienna Patients with type 2 diabetes improved control of their blood sugar, lost weight and reduced their blood pressure with a new Novo Nordisk liraglutide [...]
Drs Brian O’Shea, Catherine McCollam, Marjorie Stokes and John Yek discuss how diabetes mellitus can impact on a patient’s mental health and well-being The diabetic way of life brings its own particular stresses, and diabetes mellitus (DM) has direct effects on the nervous system. A diagnosis of DM may elicit anger, anxiety, depression, social withdrawal, [...]
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