February 8, 2012

Managing hypertension in diabetic patients

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Prof Eoin O’Brien looks at the benefits of aliskiren in the treatment of hypertension but says it should not be prescribed with ACE inhibitors or ARBs in diabetic patients.

Heart failure increases osteoporotic fracture risk

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Analysis of a large Canadian database has confirmed a link between heart failure and osteoporotic fractures but showed for the first time it is independent of bone mineral density (BMD).

Why LDL cholesterol is atherogenic

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Prof Gerald H Tomkin provides an overview of the role played by LDL and the correlation between LDL cholesterol levels and atherosclerotic risk.

Gene analysis helps identify basis of rare infant heart-disorder

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Researchers are closing in on a rare genetic disorder causing a heart condition in infants. Histiocytoid cardiomyopathy (HC) often causes sudden death before a child reaches two years of age. Gene analysis is helping to narrow the many theories surrounding the genetic basis of HC.

CVD patients particularly vulnerable to CAM

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Cardiovascular disease (CVD) patients might be particularly vulnerable to the effects of complementary and alternative medicine (CAM), cardiologists say.

Risk is controlled if obese kids achieve normal adult weight

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People who are obese in childhood but are of normal weight as adults have similar cardiovascular risks to an individual who has a normal weight both as a child and an adult, new research has shown.

MTX reduces cardiovascular risk in RA patients

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Methotrexate (MTX) appears to reduce the risk of cardiovascular disease (CVD) in patients with conditions such as rheumatoid arthritis (RA), a systematic review finds, supporting the inflammatory hypothesis of atherothrombosis.

Elderly can be suitable for CABG

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The notion that being over 70 years puts patients undergoing coronary artery bypass graft (CABG) at increased risk of stroke has been challenged by a large study, which suggests the burden of atherosclerosis plays a more important role.

CKD — adverse cardiovascular outcomes must be addressed

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Consultant nephrologist Prof George Mellotte informed a recent Dublin meeting that appropriate primary-care management of patients with chronic kidney disease may reduce overall cardiovascular risk and delay progression to renal failure, reports Gary Culliton.

Glycaemic control link to ischaemic stroke

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In ischaemic stroke patients, HbA1c on admission was an independent significant predictor for neurological and functional outcomes, Prestroke glycemic control is associated with the functional outcome in acute ischemic stroke — a study by Dr Masahiro Kamouchi et al based at the Department of Medicine and Clinical Science in Kyushu University, Fukuoka, Japan — has [...]

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