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April 29, 2016

3D DBT better than just digital mammography

A new study of breast cancer screening, published online by JAMA Oncology, suggests 3D digital breast tomosynthesis (DBT) outcomes were sustainable with significant reduction in patient recall, increasing cancer cases per recalled patients and a decline in interval cancers.

Outcomes with new agents outlined

An individual approach to breast cancer treatment is now preferred, Gary Culliton reports in his latest Clinical Update. The way drugs are administered and scheduled is now much more specific to the type of disease involved.

Testing of BRCA1 and BRCA2 on the rise in those under-40

Rates of genetic testing for the BRCA1 and BRCA2 gene mutations have increased among women diagnosed with cancer aged 40 years and under, US research has found.

Caregiving has major financial impact

Head and neck cancer can have a serious and long-lasting financial and emotional impact, not just on the patients alone, but also on their carers who are often older and poorer, according to a new research by the National Cancer Registry (NCRI), published in the Journal of Psycho-Oncology.

Novel protein target could help find dormant cancer stem cells

A novel protein target that could help identify cancer stem cells while they are dormant has been discovered by scientists at Trinity College, Dublin.

Childhood cancer survivors are at higher risk of autoimmune diseases

Childhood cancer survivors are at heightened risk of a wide range of autoimmune diseases, reveals research published online in the Annals of the Rheumatic Diseases, with diabetes and Addison’s disease making up almost half of the excess cases.

Ultrasound can aid breast cancer screening

Adding ultrasound to standard mammography tests in breast screening could result in improved rates of detection for breast cancer in women in Japan, according to a new study published in The Lancet.

Gene linked to risk of bowel cancer recurrence

Scientists have discovered a new gene linked to an increased risk of bowel cancer recurrence and shortened survival, reveals research in the journal Gut.

Superlatives for cancer drugs are overused

The use of superlatives to describe cancer drugs in news articles as “breakthrough,” “revolutionary,” “miracle” or in other grandiose terms is common, even when drugs are not yet approved, have no clinical data or do not yet show overall survival benefits, according to an article in JAMA Oncology.

Use of laparoscopic resection is not supported

Among patients with stage II or III rectal cancer, the use of laparoscopic resection compared with open resection fails to meet the criterion for non-inferiority for pathologic outcomes, according to research published in JAMA.

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