Combined therapy with adapted interpersonal psychotherapy (IPT) was superior to an antidepressant (AD) alone in patients with borderline personality disorder (BPD), concerning a few core symptoms of the disorder, anxiety and quality of life, new research has concluded. Combined treatment with IPT and ADs has been found more effective than single pharmacotherapy in patients with [...]
Dr Dmitri Wall and Prof Sarah Rogers look at the different clinical types of psoriasis and examine the many treatment options, including topical treatments, phototherapy, systemic therapy and biologic agents Psoriasis is a chronic dermatosis characterised by red scaly patches which classically occur on extensor aspects of the limbs. Psoriasis is most prevalent in the [...]
Alcohol is an increasingly important factor in the rising toll of fatal car crashes involving young women drivers, according to new research from the United States. In 2007 alone, alcohol-related fatal car crashes accounted for almost a third of the total in the US. Against that background, researchers analysed data from the National Highway Traffic [...]
Women with breast cancer who take the antidepressant paroxetine at the same time as tamoxifen are at an increased risk of death, a new Canadian study has found. Antidepressants are of particular importance because they are commonly used in women with breast cancer, often for long periods of time. Although many antidepressants have little or [...]
Early treatment of ocular hypertension appears to reduce the risk of developing glaucoma, especially in individuals at the highest risk, according to a new study. The authors added, however, that such a strategy may not offer an absolute benefit in individuals at low risk. Doctors compared the safety and efficacy of earlier versus later treatment [...]
Factors such as maternal high blood pressure and high haematocrit levels are associated with a greater likelihood of restricted foetal growth during the first trimester and increased risk of preterm birth and low birth weight, according to a new Dutch-led study. Doctors led by Dr Dennis O. Mook-Kanamori of the Erasmus Medical Centre, Rotterdam, examined [...]
Two new studies have shown that obesity and alcohol act together to increase the risk of liver disease in both men and women. Rates of liver disease and obesity are increasing. While alcohol is a major cause of liver cirrhosis, recent evidence suggests that excess body weight may also play a role. In the first [...]
In the FIT Long Term Extension (FLEX) trial, ten years of alendronate (ALN) did not significantly reduce the risk of non-vertebral fractures (NVF), compared with five years of treatment. However, continuing ALN reduced the risk of clinical, but not morphometric, vertebral fractures, regardless of baseline vertebral fracture status. In previous studies, ALN efficacy for NVF [...]
Inhaled corticosteroid (ICS) could be a better choice as an initial asthma therapy during maximum allergen exposure in children with newly diagnosed asthma. A new paper from Polish researchers has evaluated the effects of ICS in two different doses and montelukast sodium on clinical symptoms and lung function in children with newly diagnosed asthma. The [...]
Ticagrelor seems to be a better option than clopidogrel for patients with acute coronary syndromes for whom an early invasive strategy is planned, a new study has suggested. Variation in and irreversibility of platelet inhibition with clopidogrel has led to controversy about its optimum dose and timing of administration in patients with acute coronary syndromes. [...]
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