An air of defeatism exists within the medical profession about chronic fatigue syndrome that is undermining evidence that it can be treated, according to leading doctors in the field. The recent acquittal in Britain of Kay Gilderdale, who had been charged with the attempted murder of her 31-year-old daughter Lynn, has led to blanket press [...]
Chronic migraineurs sicker and poorer than episodic sufferers
Chronic migraine sufferers tend to be in poorer general health, less well off, and more depressed than those with episodic migraine, reveals research published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry. The findings are based on almost 12,000 adults with episodic — a severe headache on up to 14 days of [...]
Performing single ultrasound to detect DVT may be sufficient
An analysis of previous studies has suggested that for patients with a suspected deep vein thrombosis (DVT), withholding anticoagulation therapy after a negative whole-leg compression ultrasound is associated with a low risk of developing a DVT during the subsequent three months. Compression ultrasound (CUS) is the primary testing procedure used to diagnose proximal deep vein [...]
Age may affect efficacy of antiresorptive drugs
Patient age may affect the relative efficacy of oral bisphosphonates in postmenopausal women, research has suggested. A team from the VCU Medical Center in Richmond, Virginia, carried out a post-hoc analysis of postmenopausal women /=55 years old with low bone mineral density (BMD), randomised to once weekly alendronate 70mg or risedronate 35mg for one year [...]
Effective alternative for emergency contraception
The emergency contraceptive drug ulipristal acetate provides women and healthcare providers with an effective alternative that can be used up to five days after unprotected sexual intercourse, a study in The Lancet has stated. Emergency contraception can prevent unintended pregnancies, but current methods are only effective if used as soon as possible after sexual intercourse [...]
Genetic mutations link with suicide in depression
Single mutations in genes involved with nerve cell formation and growth appear to be associated with the risk of attempting suicide among individuals with depression, according to a new report. Doctors led by colleagues at the Max Planck Institute of Psychiatry, in Munich, Germany investigated genetic variants among 394 depressed patients, including 113 who had [...]
Hypertension link to dementia in certain cognitive deficits
High blood pressure appears to predict the progression to dementia in older adults with impaired executive functions but not in those with memory dysfunction, according to a new report. In light of evidence that hypertension is a major risk factor for vascular brain diseases and vascular cognitive impairment, researchers postulated that the cognitive domain of [...]
Proteinuria linked to increased mortality
Patients with high levels of proteinuria in addition to another marker of reduced kidney function had an associated increased risk of all-cause death, heart attack or progression to kidney failure, according to a new study. Doctors investigated the association between reduced glomerular filtration (eGFR), proteinuria and adverse clinical outcomes, including all-cause death, heart attack and [...]
Impact of PPI on antiplatelet activity of clopidogrel
Careful treatment planning is required when administering omeprazole, a proton pump inhibitor (PPI), to patients on clopidogrel, new research has recommended. PPI use with clopidogrel was recently shown to result in increased risk of major cardiovascular events compared to clopidogrel use alone. A team from Wonkwang University Hospital, South Korea, evaluated the effects of omeprazole, [...]
Narcolepsy hugely underdiagnosed
Sleep disorders were the focus of a recent symposium held as part of the Irish Thoracic Society’s Annual Scientific Meeting, writes Suzanne McCormack Two studies – ‘Obstructive Sleep Disorders and Driving Risk’ and a ‘National Survey of Narcolepsy in Ireland’ – highlighted the under-diagnosis of sleep disorders in Ireland, the lack of resources in this [...]