There have been many changes in advanced kidney cancer over the past decades. Until recent times, this had not included any improvement in survival. During these years, a greater understanding of the genetic basis and potential molecular targets has yielded therapeutic interventions with very significant improvement in tumour control and longer survival. Through more careful [...]
Systemic treatment of psoriasis
Dr Benvon Moran and Prof Sarah Rogers explain the range of systemic treatments available for patients with psoriasis in the first part of a two-part article and discuss dosage, side-effects and monitoring. (Part 2 next week). Psoriasis affects one per cent to three per cent of people in Europe and so almost 100,000 people in [...]
Keeping a watch on eye health
A new UK online prevalence model is helping clinicians and health planners to improve patient services for those affected by four major eye conditions. UK health planners and clinicians can now improve patient services and anticipate the changes when new treatments become available, thanks to a new online prevalence model for four major eye conditions. [...]
Kids who live with smokers less likely to get good food
Children and adults living with adult smokers appear less likely to have daily access to enough healthy food compared with those living with non-smoking adults, according to a new report. The report followed a study in which American doctors analysed 8,817 households with children to see if the presence or absence of adult smokers in [...]
Precipitation levels may be associated with autism
Children living in counties with higher levels of annual precipitation appear more likely to have higher prevalence rates of autism, according to a new report. The results raise the possibility that an environmental trigger for autism may be associated with precipitation and may affect genetically vulnerable children. In the study, doctors obtained autism prevalence rates [...]
Folic acid, B vitamins do not appear to affect cancer risk
A daily supplementation combination that included folic acid and vitamin B6 and B12 had no significant effect on the overall risk of cancer, including breast cancer, among women at high risk of cardiovascular disease, according to a new study. In the study, doctors evaluated the effect of combined folic acid, vitamin B6 and vitamin B12 [...]
Diabetes questions answered
Continuing our Ask the Consultant series, Prof Gerald Tomkin answers questions from general practitioners on diabetes and how best to treat the condition. 1. Is there a case for advocating earlier insulin introduction in the poorly controlled type 2 diabetic? Answer: This is an important question and one which immediately gets to the heart of [...]
Management of rectal cancer
Dr Julian Tsang and Mr Eadhbhard Mulligan, of the Hermitage Medical Clinic, writes about the challenges of treating rectal cancer, which accounts for 30 per cent of all colorectal cancers. Surgical resection is the principal treatment modality in rectal cancer. One of the main determinants of treatment success is the occurrence of local recurrence, characterised [...]
Klinefelter’s syndrome: a male infertility disorder
Dr Muhammad Arshad and Prof Michael Fitzgerald write about the causes of and the treatment options for Klinefelter’s syndrome, a trisomy disorder that is found in approximately one in 700 male births. Klinefelter’s syndrome (KS) is the most common cause of hypogonadism and the second most common trisomy disorder. It was named after Dr Harry [...]
Study brings hope for Parkinson’s
Results from a new study have the potential to change the way Parkinson’s disease (PD) is treated, delegates at the 12th Congress of the European Federation of Neurological Societies in Madrid heard in August. The results from the ADAGIO (Attenuation of Disease progression with Azilect Given Once-daily) trial, revealed at a Late Breaking News session, [...]