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Clinical Times: August 2008
Targeted therapy is the way forward for NSCLC
Rory Hafford | 29 August 2008 | Cancer
Rory Hafford talks to Prof Thomas Lynch about his research into one of the world’s leading causes of cancer mortality and he finds that a new approach is having a positive impact on survival rates in non-small cell lung cancer.... Read more
Early-life nutrition is linked to intellectual functioning in adults
Archives of Pediatrics and Adolescent Medicine | 29 August 2008 | Nutrition
Adults who had improved nutrition in early childhood may score better on intellectual tests, regardless of the number of years they attended school, according to a new report. Between 1969 and 1977, Guatemalan children in four villages participated in a... Read more
HDL: the good cholesterol?
Prof Gerald H. Tomkin | 28 August 2008 | Cardiovascular
Prof Gerald H. Tomkin writes about the connections between the levels of LDL and HDL cholesterols and a patient's risk of developing coronary artery disease. The story of cholesterol is long and fascinating. One of the reasons why cholesterol became... Read more
Physical activity is shown to steadily decline as children age
JAMA | 28 August 2008 | Musculoskeletal
New research documents the decline in physical activity among children, with less than a third meeting recommended physical activity guidelines by the time they are 15 years old, according to a new study. Expert opinion and studies suggest that children... Read more
A manifesto for the future of dementia care services
Mary Anne Kenny | 27 August 2008 | Mental Health & CNS
A diagnosis of dementia or Alzheimer’s disease can feel devastating for the person affected and for that person’s family and friends. Receiving a diagnosis of any serious illness is an isolating experience – nobody else in the world feels as... Read more
Recent progress in neonatology
27 August 2008 | Nutrition
Dr Kate Bruton and Dr David Corcoran write about advances made in the field of neonatology, which have gradually reduced the threshold for viability of preterm infants Preterm infants born without respiratory distress have been surviving with incubator care and... Read more
Fewer psychiatrists are also delivering psychotherapy
Archives of General Psychiatry | 27 August 2008 | Mental Health & CNS
A declining number of office-based psychiatrists appear to be providing psychotherapy to their patients, according to a new report from the United States. According to the report, doctors analysed trends in psychotherapy provision using data from national surveys of office-based... Read more
Barrett's oesophagus and the battle of the bulge
Gary Culliton | 20 August 2008 | Cancer
Gary Culliton reports on recently published research carried out in Trinity College Dublin, which investigated the links between 'beer belly' fat and the development of cancer Breakthrough research at Trinity College Dublin has described one of the mechanisms through which... Read more
Learning medicine and the factors that form a medical brain
Mike Power | 20 August 2008 | Mental Health & CNS
Mike Power, Research Psychologist, continues his series of articles on the stresses and pressures faced uniquely in the medical profession How many readers would still choose the same vocation if they had life to live over? Most of the doctors... Read more
Low-fat diet does not reduce risk of diabetes, new study concludes
Archives of Internal Medicine 2008;168:1500-1511 | 19 August 2008 | Diabetes
Eating a low-fat diet does not appear to be associated with any change in diabetes risk, according to a new study. In the study, researchers investigated the effects of eating a low-fat diet on diabetes risk in 48,835 post-menopausal women.... Read more
The value of using evidence in medicine
Dr John Wallace | 19 August 2008 | Mental Health & CNS
Dr John Wallace looks at some common criticisms of the evidence-based approach to medicine and also discusses some of its merits Doctors often underestimate the information they need to deal successfully with a patient’s problem. Even when they realise that... Read more
No justification for denying knee replacements to obese patients
http://press.psprings.co.uk/ard/july/ar93229.pdf | 18 August 2008 | Musculoskeletal
There is no justification for denying obese patients knee replacement surgery; they benefit almost as much as anyone else from the procedure, concludes a small study published ahead of print in the Annals of the Rheumatic Diseases. Around 55,000 knee... Read more
Dementia heading for population time bomb
Dr Dermot Walsh | 18 August 2008 | Mental Health & CNS
Dr Dermot Walsh of the Mental Health Research Unit of the Health Research Board forecasts an explosion in the costs of caring for people with dementia The Central Statistics Office has just produced its Population and Labour Force Projections to... Read more
Athletes continue to take caffeine to enhance their performance
http://press.psprings.co.uk/bmj/july/caffeine.doc | 17 August 2008 | Cardiovascular
A study of UK athletes has revealed that 33 per cent of track and field athletes and 60 per cent of competitive cyclists take caffeine to enhance performance. Four years ago, the World Anti-Doping Agency (WADA) removed caffeine from the... Read more
Athletes continue to take caffeine to enhance their performance
http://press.psprings.co.uk/bmj/july/caffeine.doc | 17 August 2008 | Cardiovascular
A study of UK athletes has revealed that 33 per cent of track and field athletes and 60 per cent of competitive cyclists take caffeine to enhance performance. Four years ago, the World Anti-Doping Agency (WADA) removed caffeine from the... Read more
Managing chronic diseases in general practice surgeries
Dr Velma Harkins | 17 August 2008 | Diabetes
Dr Velma Harkins writes that our ageing demographic will mean a consequent increase in chronic diseases and that these must be managed in general practice Chronic diseases tend to be complex conditions in how they are caused. They are often... Read more
Loss of cannabinoid receptor accelerates tumour growth
Cancer Res 2008 68(15):6468–76 | 16 August 2008 | Cancer
A cannabinoid receptor lying on the surface of cells may help suppress colorectal cancer, say US researchers. When the receptor is turned off, tumour growth is switched on. Cannabinoids are compounds related to the tetrahydrocannabinol (THC) found in the cannabis... Read more
New trials offer hope to Irish patients
Derbhile Dromey | 16 August 2008 | Cancer
Derbhile Dromey reports on the clinical trials carried out by ICORG, which give Irish patients access to the very latest in drug treatments The treatment of stage four cancer patients with drugs at the Phase I stage has evolved significantly... Read more
Modern thinking on gait disorders
Dr Aishling Murray and Prof Desmond O’Neill | 15 August 2008 | Musculoskeletal
Dr Aishling Murray and Prof Desmond O’Neill give a practical guide on how to diagnose and manage gait disorders in older people Gait disorders are common among older people, but until recently have been overlooked as a treatable medical syndrome.... Read more
Stroke care needs major investment
Dr Joe Harbison | 15 August 2008 | Cardiovascular
Dr Joe Harbison looks at definitions of stroke care and where Ireland stands relative to other countries. Stroke unit management is such a basic level of care that its absence in many countries would be considered negligent. We have now... Read more
There is a place for ECT in today's psychiatry
Dr Seán Ó Domhnaill | 14 August 2008 | Mental Health & CNS
Dr Seán Ó Domhnaill writes that refusing to consider the possibility that older treatments like ECT can be of benefit demonstrates a kind of 'therapeutic blindness' “There can be no place in psychiatry for those who would refuse treatments with... Read more
Sugar-sweetened beverages associated with diabetes risk
Archives of Internal Medicine 2008;168:1487-1492 | 09 August 2008 | Diabetes, Nutrition
Drinking more soft drinks and fruit drinks is associated with an increased risk for diabetes, a new study has found. In the study, researchers examined the association between type 2 diabetes, weight gain and the consumption of sugar-sweetened soft drinks... Read more
Reduced intake of fruit and vegetables linked to bigger diabetes risk
08 August 2008 | Diabetes, Nutrition
Eating fewer fruits and vegetables may be associated with an increased risk of type 2 diabetes, according to a new study. In the study, researchers analyzed blood vitamin C levels and fruit and vegetable intake in 21,831 individuals who did... Read more
Exercise advice is not enough for overweight women
Archives of Internal Medicine 2008;168:1550-1559 | 07 August 2008 | Nutrition, Women's Health
In addition to limiting calories, overweight and obese women may need to exercise 55 minutes a day for five days per week to sustain a weight loss of 10 per cent over two years, according to a new report. In... Read more
More people taking part in sport but ...
06 August 2008 | Men's Health, Women's Health
... the gap between rich/poor and black/white remains The comfortably off, white, and middle-aged are the most likely to participate in sporting activities, a new 10-year UK study has revealed. Furthermore, the gap between rich and poor — and black... Read more
How to treat early onset arthritis
Dr Joanne Kitchen and Dr David Kane | 06 August 2008 | Musculoskeletal
Dr Joanne Kitchen and Dr David Kane from AMNCH's Department of Rheumatology explain how to treat patients with early onset arthritis. Rheumatoid arthritis is a chronic, systemic, inflammatory disorder of unknown aetiology that primarily involves joints. It can be a... Read more
Increase in number of people who fail to recognise they are overweight
BMJ Online First | 02 August 2008 | Nutrition
More and more people are failing to recognise they are overweight, despite an actual rise in the number of people who are clinically overweight or obese, according to new research. Researchers from the Health Behaviour Research Centre at University College... Read more
Raised level of protein is linked to risk of diabetes in elderly
JAMA 2008;300:182-188 | 01 August 2008 | Diabetes
Having a higher than normal level of the protein fetuin-A is associated with an increased risk of the development of diabetes, according to a new study. In the study, doctors examined whether higher fetuin-A levels are associated with the occurrence... Read more