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August 22, 2014

Resistant hypertension and the role of spironolactone in its treatment

Resistant hypertension is diagnosed in individuals who are actually taking their medicines but despite three antihypertensives (in the US they recommend one should be a diuretic) BP remains stubbornly above goal >140/90 mmHg. For many years we had intermittently used spironolactone. In the late 1980s following unpublished evidence, suggesting that a chemically similar compound caused […]

Intensive training of young tennis players may lead to arthritis

The intensive training given to young elite tennis players damages their spines and may lead to arthritis, according to new research from the UK. Magnetic resonance imaging scans of young elite tennis players with no symptoms of pain showed a variety of spinal abnormalities in the lower back, some of which were irreparable.The scans picked […]

Knee arthritis link to lung cancer

Arthritis of the knee may be the first sign of non-small cell lung cancer in heavy smokers, novel research from Italy has found. The researchers reviewed the case notes of all patients with rheumatic disorders, diagnosed at one tertiary referral centre over six years. Between 2000 and 2005, more than 6,500 new patients attended the […]

Family-based treatment better than psychotherapy for bulimia

Bulimia patients aged 12 to 19 years who received family-based treatment were less likely to continue to binge and purge than those who received supportive psychotherapy that explored the underlying issues of the disorder, according to a new report. In the study, American researchers analysed 80 patients – 37 with bulimia and 43 with bulimic […]

Food supplements to treat diabetes and atherosclerosis

The health benefits of cutting down on dietary saturated fatty acids and including higher levels of unsaturated fatty acids are well documented in medical literature. Nutritional research is focusing on the effects of incorporating these healthier fatty acids, such as conjugated linoleic acid (CLA), into animal and human diets. CLA is present in dairy products […]

Heart attack patients at higher risk of developing diabetes

People who have had heart attacks are at higher risk of developing both new-onset diabetes and impaired fasting glucose (IFG), a new study has found. In the study, doctors investigated 8,291 Italian patients who had had a heart attack within the previous three months, and were free of diabetes. Incidence of new-onset diabetes and IGF […]

European Hypertension Guidelines: Comprehensive and worthwhile

The 2007 guidelines for the management of arterial hypertension from the European Societies of Hypertension and Cardiology have just been published in the Journal of Hypertension (2007;25:1105-87). These update the 2003 guidelines and were eagerly awaited particularly because of the apparent shift in direction seen in the recent British/NICE 2006 guidelines, which favours a minimalist […]

Novel approaches for the treatment of chronic gout

Gout needs no introduction. It is characterised by the abnormal deposition of urate crystals as a result of hyperuricaemia. The diagnosis rests on the identification of crystals in tissue or synovial fluid. Gout presents initially with intermittent attacks of acute arthritis, which may subsequently progress to chronic tophaceous disease. With increased understanding of these mechanisms […]

Coming to terms with Tourette’s, part three

It has been found that 12 per cent of Tourettes’s syndrome patients have no co-morbidity, which means 88 per cent show association with ADHD, OCD, anxiety, and affective disorders. Corbett et al (1969) reported that 31 per cent (57/184) TS individuals had a family history of psychiatric illness. Generalised tics were found in 64.1 per […]

Not all probiotic products effective against diarrhoea

Several probiotic products are marketed as effective treatments for acute diarrhoea in children, but a new study has found that not all of these preparations are effective. In the study, researchers at the University of Naples tested five different preparations in 571 children with acute diarrhoea. All the children were aged three to 36 months […]

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