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May 24, 2013

Low testosterone may herald RA in men

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Low testosterone levels may herald the subsequent development of rheumatoid arthritis (RA) in men, suggests research published recently in the Annals of the Rheumatic Diseases.

Genetic basis is revealed for ataxia, dementia and hypogonadotropism

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A new study in the New England Journal of Medicine has highlighted a hitherto unknown role of the ubiquitination system in disorders of combined neurodegeneration and reproductive dysfunction.

TRT may enhance endothelial function in hypogonadal men

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Testosterone replacement therapy (TRT) can increase the number of circulating endothelial progenitor cells (EPCs) in hypogonadal men, and thus may have a benefit on endothelial function and possibly coronary artery disease, Taiwanese research suggests.

Gene mutations and hypogonadotropic hypogonadism

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The FGF17 and IL17RD genes are the two top candidates in the entire proteome that may contribute to the genetics of congenital hypogonadotropic hypogonadism (CHH), new research has found.

Survivors’ increased prevalence of metabolic syndrome

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Testicular germ cell tumour survivors have an increased prevalence of the metabolic syndrome (MetS), with hypogonadism and combination chemotherapy (CT) treatment being clear risk factors for the development of the syndrome.

Learning to breathe under water… and more

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Marie-Catherine Mousseau reports on ways to improve the quality of life of both carers and patients, as presented at the 8th Annual Palliative Care Symposium.

Clinical update on depression

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In his latest Clinical Update, Gary Culliton examines the rating scales and classification systems used in clinical diagnoses of depression, as well as the range of treatment options now available.

Clinical update on breast cancer

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There is significant evidence linking obesity to breast cancer incidence. In his latest Clinical Update, Gary Culliton reports on breakthrough research in susceptible women.

Antipsychotics: managing medical crises

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Dr Muhammad Arshad, Consultant Child and Adolescent Psychiatrist at Hawkes Bay District Hospital, New Zealand, and Prof Michael Fitzgerald, Henry Marsh Professor of Child Psychiatry, TCD, on the use of antipsychotics.

New implanted device can predict epilepsy seizures

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For the first time, a small device implanted in the brain has accurately predicted the onset of seizures in some adults who have epilepsy that does not respond to drugs, according to a small proof-of-concept study published online first in The Lancet Neurology.

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