February 4, 2012

GP management of shoulder issues

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Edel Comer and Victoria Percy look at the physiotherapy management of common shoulder-joint problems in the primary care setting.

FRAX the more clinically relevant measure

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In his latest Clinical Update, Gary Culliton examines recent developments in the field of osteoporosis, including diagnostic tools and issues related to glucocorticoids.

Increasing placebo response destroys evidence of benefit

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Despite older tricyclic antidepressants demonstrating a significantly greater efficacy over newer drugs, a major 30-year meta-analysis concludes the differences are largely a result of changes in trial designs, leading to greater placebo response and lower drug response.

Bipolar masked as medication-resistant depression

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The idea that patients who present with medication-resistant depression could be harbouring a hidden bipolar disorder has been bolstered by the largest study of the topic so far.

Heart failure increases osteoporotic fracture risk

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Analysis of a large Canadian database has confirmed a link between heart failure and osteoporotic fractures but showed for the first time it is independent of bone mineral density (BMD).

Capsaicin beats cannabis in RA treatment

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The adverse side effects of most neuromodulators and muscle relaxants overshadow any pain relief potential in rheumatoid arthritis (RA), a new Cochrane Review finds.

Vitamin D supplements are advised with steroids

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Most patients taking steroids have suboptimal vitamin D levels and should take supplements to prevent drug-induced osteoporosis, experts have advised.

Dental issues are common with port wine stains

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Patients with facial port wine stains (PWS) are at an increased risk of dental complications, particularly gingival staining, a study has confirmed.

Newborn infants face doubled risk with SSRIs

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Infants born to mothers who take SSRIs during face more than twice the risk of pulmonary hypertension compared with unexposed infants, research has found.

Evidence links IBD development to colder weather

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New research has identified a link between warmer climates and lower incidences of Crohn’s disease (CD) and ulcerative colitis (UC).

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